Dosimetry Evaluation of Custom Made Eye Plaque for Brachytherapy of Ocular Melanoma

Custom Made Mold Brachytherapy

A reanalysis of the Collaborative Ocular Melanoma Study Medium Tumor Trial eye plaque dosimetry.

PURPOSE To recalculate the radiation doses delivered to structures of interest within the eye, i.e., the lens, tumor apex, 5-mm point, optic disk, and macula for patients treated with eye plaque radiotherapy on the Collaborative Ocular Melanoma Study (COMS) Medium Tumor Trial, using updated dosimetric data. METHODS AND MATERIALS Using the Plaque Simulator planning system, doses were recalcula...

Dosimetry Comparison of Water Phantom and Complete Eye Definition for 125I and 103Pd Brachytherapy Plaques

Introduction: In this paper, by complete definition of human eye containing the various parts and their materials, the difference between this model and a homogeneous water phantom are compared for two ophthalmic plaques using 125I and 103Pd. Material and methods: The simulation of the two phantoms were performed in the MCNP-4C code and by using the geometry of a three-dimensional eye, differen...

ROPES eye plaque dosimetry: commissioning and verification of an ophthalmic brachytherapy treatment planning system

In this study, the Plaque SimulatorTM eye plaque brachytherapy planning system was commissioned for ROPES eye plaques and Amersham Health model 6711 Iodine 125 seeds, using TG43-UI data. The brachytherapy module of the RADCALC® independent checking program was configured to allow verification of the accuracy of the dose calculated by Plaque SimulatorTM. Central axis depth dose distributions wer...

Monte Carlo dosimetry of the eye plaque design used at the St. Erik Eye Hospital for (125)I brachytherapy.

PURPOSE At St. Erik Eye Hospital in Stockholm, Sweden, ocular tumors of apical height above 6 mm are treated with brachytherapy, using iodine-125 seeds attached to a gold alloy plaque while the treatment planning is performed assuming homogeneous water surroundings. The aim of this work was to investigate the dose-modifying effects of the plaque and the seed fixating silicone rubber glue. MET...